Ramesh Sharma Selected Research

Centchroman

12/2019	Genistein potentiates Centchroman induced antineoplasticity in breast cancer via PI3K/Akt deactivation and ROS dependent induction of apoptosis.
2/2018	Dietary isoflavone daidzein synergizes centchroman action via induction of apoptosis and inhibition of PI3K/Akt pathway in MCF-7/MDA MB-231 human breast cancer cells.
4/2017	Centchroman induces redox-dependent apoptosis and cell-cycle arrest in human endometrial cancer cells.
11/2016	Genistein synergizes centchroman action in human breast cancer cells.
1/2012	Polyphenols sensitization potentiates susceptibility of MCF-7 and MDA MB-231 cells to Centchroman.
12/2010	Centchroman mediated apoptosis involves cross-talk between extrinsic/intrinsic pathways and oxidative regulation.
3/2008	Centchroman induces G0/G1 arrest and caspase-dependent apoptosis involving mitochondrial membrane depolarization in MCF-7 and MDA MB-231 human breast cancer cells.

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Ramesh Sharma Research Topics

Disease

13	Breast Neoplasms (Breast Cancer) 12/2019 - 03/2006
9	Neoplasms (Cancer) 02/2018 - 12/2002
4	Body Weight (Weight, Body) 08/2013 - 08/2010
2	Seizures (Absence Seizure) 07/2020 - 01/2020
2	Malnutrition (Nutritional Deficiencies) 08/2017 - 08/2016
2	Neurodegenerative Diseases (Neurodegenerative Disease) 12/2011 - 12/2011
1	Gliosis 01/2022
1	Hyperalgesia 01/2022
1	Hypersensitivity (Allergy) 01/2022
1	Neuralgia (Stump Neuralgia) 01/2022
1	Pain (Aches) 01/2022
1	Peripheral Nervous System Diseases (PNS Diseases) 01/2022
1	COVID-19 12/2021
1	Mitochondrial Diseases (Mitochondrial Disease) 12/2019
1	Congenital Methemoglobinemia 06/2018
1	Endometrial Neoplasms (Endometrial Cancer) 04/2017
1	Wounds and Injuries (Trauma) 07/2012
1	Experimental Diabetes Mellitus 03/2012
1	Inflammation (Inflammations) 08/2011
1	Cardiotoxicity 04/2009
1	Adenocarcinoma 12/2006
1	Glioma (Gliomas) 10/2006
1	Carcinogenesis 07/2006
1	Breast Diseases (Breast Disease) 07/2006
1	Arsenic Poisoning 06/2004

Drug/Important Bio-Agent (IBA)

7	CentchromanIBA 12/2019 - 03/2008
4	CurcuminIBA 08/2013 - 08/2010
3	IsoflavonesIBA 12/2019 - 11/2016
3	Proteins (Proteins, Gene)FDA Link 12/2011 - 12/2002
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2022 - 07/2017
2	gamma-Aminobutyric Acid (GABA)IBA 01/2022 - 01/2020
2	Pharmaceutical PreparationsIBA 12/2021 - 04/2009
2	GenisteinIBA 12/2019 - 11/2016
2	Oral ContraceptivesIBA 02/2018 - 11/2016
2	Estrogens (Estrogen)FDA Link 04/2017 - 12/2006
2	ormeloxifeneIBA 04/2017 - 11/2016
2	MelatoninIBA 08/2013 - 12/2011
2	Dimethyl Sulfoxide (DMSO)FDA LinkGeneric 08/2013 - 08/2010
2	EnzymesIBA 03/2012 - 12/2011
2	ResveratrolIBA 01/2012 - 05/2011
2	Antineoplastic Agents (Antineoplastics)IBA 01/2012 - 12/2010
2	Hormones (Hormone)IBA 01/2012 - 03/2006
2	Cyclophosphamide (Cytoxan)FDA LinkGeneric 05/2011 - 04/2009
2	IodineIBA 07/2006 - 12/2002
1	Analgesics (Analgesic Drugs)IBA 01/2022
1	Monoamine Oxidase (MAO)IBA 01/2022
1	Monoamine Oxidase Inhibitors (Monoamine Oxidase Inhibitor)IBA 01/2022
1	Paclitaxel (Taxol)FDA LinkGeneric 01/2022
1	CenobamateIBA 07/2020
1	Anticonvulsants (Antiepileptic Drugs)IBA 07/2020
1	Caspase 3 (Caspase-3)IBA 12/2019
1	GlobinsIBA 06/2018
1	daidzeinIBA 02/2018
1	steviolIBA 07/2017
1	lissamine rhodamine B (sulforhodamine B)IBA 07/2017
1	DNA (Deoxyribonucleic Acid)IBA 07/2017
1	Contraceptive Agents (Contraceptives)IBA 04/2017
1	neem oilIBA 01/2017
1	Selective Estrogen Receptor Modulators (SERM)IBA 11/2016
1	LigandsIBA 07/2012
1	Insulin (Novolin)FDA Link 07/2012
1	Bovine Serum AlbuminIBA 07/2012
1	MitogensIBA 07/2012
1	Thiobarbituric Acid Reactive SubstancesIBA 03/2012
1	Free RadicalsIBA 03/2012
1	AntioxidantsIBA 03/2012
1	PolyphenolsIBA 01/2012
1	Ascorbic Acid (Vitamin C)FDA LinkGeneric 12/2011
1	Mitogen-Activated Protein KinasesIBA 08/2011
1	Oxygen (Dioxygen)IBA 08/2010
1	A-Form DNA (A-DNA)IBA 04/2009
1	Alkylating AgentsIBA 04/2009
1	Estrogen ReceptorsIBA 03/2008
1	RetinoidsIBA 10/2006
1	Tretinoin (Retinoic Acid)FDA LinkGeneric 10/2006
1	FenretinideIBA 10/2006
1	CaspasesIBA 07/2006
1	Methylnitrosourea (N-Methyl-N-nitrosourea)IBA 07/2006
1	PhenanthrenesIBA 03/2006
1	Tamoxifen FDA LinkGeneric 03/2006
1	anthraceneIBA 03/2006
1	ArsenicIBA 06/2004
1	Drinking WaterIBA 06/2004
1	Cytochromes c (Cytochrome c)IBA 12/2002

Therapy/Procedure

2	Diet Therapy (Therapy, Diet) 08/2017 - 08/2016
1	Oral Administration 01/2022
1	Drug Therapy (Chemotherapy) 01/2022
1	Anesthesia 06/2018
1	Therapeutics 05/2011